A pioneering advanced wound care system based on Gel4Med’s proprietary Smart Materials Platform™.
G4Derm® Plus system includes a prefilled syringe and a flexible applicator tip that enables precise delivery of the flowable biomimetic matrix to irregularly shaped and hard-to-access wounds. G4Derm® Plus forms a 3D scaffold that mimics the human extracellular matrix (ECM) and serves as an antibacterial barrier that protects the wound. The biomimetic matrix is uniquely positioned to simultaneously spur tissue regrowth and control bioburden.
G4Derm® Plus biomimetic matrix features a biodegradable scaffold that emulates the native extracellular matrix properties of human skin. This microarchitecture provides an environment conducive to tissue regrowth and revascularization to support effective wound healing.1
G4Derm Plus’s 3D matrix structure provides a non-immunogenic, antibacterial barrier that protects the wound. This matrix barrier may help reduce infection and prevent biofilm reformation.2,3
G4Derm® Plus overcomes the local tissue toxicity effects of many traditional antimicrobial wound products and offers an environment conducive to healing while keeping bacteria at bay.1,4
Together with the flexible applicator tip, the intentionally designed flowable consistency of G4Derm® Plus allows it to reach and conform to hard-to-access, irregularly shaped wound beds, while eliminating void space and remaining contained in the wound.5
G4Derm® Plus’s biomimetic properties achieved through precise molecular design combines the positive attributes of both biologics and synthetics, while overcoming their respective limitations.6
G4Derm® Plus eliminates the reliance on human and animal donor sources, which reduces the risk of biological variability while assuring reproducibility, scalability, and robust quality control of the product.
G4Derm® Plus system arrives in a prefilled, ready-to-use, sterile syringe with a flexible applicator tip, streamlining the clinical workflow without the need for thawing or mixing. The room-temperature storage capability and extended two-year shelf life7 assures consistent readiness, simplifies hospital supply chains, and offers a more cost-effective approach to storing and maintaining advanced wound care products.
1. Data on File. GM-2101. 2. Data on File. RR-0004. 3. Data on File. RR-0003. 4. Data on File. VV-0021. 5. Data on File. VV-0051. 6. Horn, Fierro, and Lantis. The Shift to Synthetics: A Review of Novel Synthetic Matrices for Wound Closure. Surg Technol Int. 2023; 7. Data on File, VV-0038.
G4Derm® Plus may be used under the direction and supervision of a health care professional (Rx), as described below:
Rx: Under the supervision of health care professionals for the local management of partial-and full-thickness wounds including pressure, and diabetic ulcers; lower extremity ulcers including those of venous, arterial, and mixed etiology; surgical wounds; first-degree and partial-thickness burns including management of abrasions and burns associated with dermabrasions and laser resurfacing.
Do not use on patients with a known sensitivity/previous allergic reaction to the product or any its components.
Key tip: Due to the shear thinning properties, drawing back the syringe plunger allows for smoother dispensing of the product.
Key tip: The applicator tip can be cut to size. It is designed to assist with hard to access space application, and may be used to assist with wound assessment.
G4M200M
00850058790022
G4Derm Plus® 3-D Peptide Matrix, medium unit
18 cm2
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"I firmly believe synthetic matrices are the future in lower extremity wound care. Synthetics offer a novel approach to managing chronic wound care that is unmatched to many currently available products. I am excited to see how the treatment landscape in lower extremity wound care evolves with the entrance of Gel4Med’s product to the market."
Dr Paul Kim, DPM
Medical Director at University of Texas Southwestern Medical Center
1660 Soldiers Field Road,
STE 7, #1063
Brighton MA 02135
M2D2 Umass Lowell, 110 Canal St, 4th Floor, Lowell MA 01852